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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

New treatments for acne scars are safer and more effective because we understand the causes better.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.

Plant-based ingredients are effective and safe for modern skincare products.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Cosmetics and procedures can cause eye issues, from mild discomfort to serious conditions, due to allergies, toxins, or poor care.

Microneedles with enhancer effectively promote hair growth and increase hair density.

L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.

The document concludes that understanding the anatomical changes of the ageing face is important for effective rejuvenation treatments.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.

Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.