research Optimization and Characterization of a Focal Dermal Hypoplasia Mouse Model to Test Potential Treatments
Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
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research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research Sodium Valproate: Doctor Jekyll and Mister Hyde
Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
research Lupus Nephritis with Visual Field Defect Secondary to Hypertensive Retinopathy: A Case Report
Visual field defects in lupus nephritis can be caused by hypertensive retinopathy, not glaucoma or medication toxicity.
research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery
Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-Small Cell Lung Cancer
A cancer patient's eyelashes grew excessively without other common side effects after taking the cancer drug erlotinib.
research Metformin or Thiazolidinedione Therapy in Polycystic Ovary Syndrome?
Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.
research Vesicles: Potential Nano Carriers for the Delivery of Skin Cosmetics
Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
research Evolution of Hair Restoration Surgery: Donor Dominance and Follicular Unit Transplantation
Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
research Alopecia Associated with Fluconazole Therapy
High doses of fluconazole can cause reversible hair loss.
research Agent: Minoxidil
Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
research Use of Mannitol Diuresis to Reduce Cisplatin Nephrotoxicity
Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.
research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism
Finasteride is a safe, effective treatment for hirsutism with fewer side effects.
research Cystoid Macular Edema in Uveitis: An Unsolved Problem
Treating cystoid macular oedema in uveitis is difficult and risky.
research Risk-Benefit Ratio in the Treatment of Psoriasis with Systemic Retinoids
Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
research High Incidence of Severe Hand-Foot Syndrome During Capecitabine-Docetaxel Combination Chemotherapy
About half the patients treated with capecitabine and docetaxel developed severe hand-foot syndrome.
research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
research Effects of Adenosine Triphosphate on Vandetanib-Induced Skin Damage in Rats
ATP helps prevent skin damage from vandetanib by reducing stress.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Ethnobotanical Study of Potentially Toxic Plants of Fez-Meknes Region, Eastern Middle Atlas, Morocco
Many people in Fez-Meknes use potentially toxic plants for various health and cosmetic purposes, but more research is needed to ensure their safety.
research Present Chemotherapy-Induced Alopecia and Future Research
Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.
research Periungual Lesions Secondary to Chemotherapy with Docetaxel
Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.
research Reporting on Adverse Clinical Events
Monitoring for adverse effects in clinical treatments is crucial.
research Efficacy and Safety of Docetaxel in the Elderly
Docetaxel is safe and works well for older people with cancer, with manageable side effects.
research Androgen Treatment in Women
Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
research Case Report: Potential Arsenic Toxicosis Secondary to Herbal Kelp Supplement
A woman's health issues were caused by arsenic poisoning from kelp supplements.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Minoxidil Overdose With ECG Changes: Case Report and Review
Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.