TLDR ATP helps prevent skin damage from vandetanib by reducing stress.
The study found that adenosine triphosphate (ATP) can prevent vandetanib-induced skin toxicity in rats by reducing oxidative stress. This suggests that ATP may be a promising treatment for preventing skin damage in humans, and further studies are needed.
192 citations
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January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause serious skin problems that need careful management.
11 citations
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September 2011 in “British Journal of Dermatology” New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.
6 citations
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December 2017 in “PubMed” Minoxidil helps hair growth by promoting stem cell differentiation through increased ATP synthase activity.
January 2023 in “Cutaneous and Ocular Toxicology” 9 citations
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June 2017 in “Pharmacological Reports” ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.