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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Oestrogens are key for bone growth during puberty in both boys and girls.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Smoking may contribute to hair loss in men.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.