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    Glossary Vitamin D Receptor

    protein that binds vitamin D to regulate gene expression

    The Vitamin D Receptor (VDR) is a protein found in various cells throughout the body that binds to vitamin D, allowing it to regulate the expression of specific genes. This receptor plays a crucial role in maintaining calcium and phosphate balance, which is essential for healthy bone formation, and it also influences immune system function and hair follicle cycling.

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    Research 30 of 1000+

    1. Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes Endocrinology · 2005 · 78 citations
    2. The Molecular Biology of the Vitamin D Receptor Humana Press eBooks · 2010 · 22 citations
    3. Minireview: vitamin D receptor: new assignments for an already busy receptor. - eScholarship 2006
    4. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    5. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008 · 127 citations
    6. Mutations in the vitamin D receptor and hereditary vitamin D-resistant rickets BoneKEy Reports · 2014 · 107 citations
    7. Quantification of the Vitamin D Receptor−Coregulator Interaction Biochemistry · 2009 · 62 citations
    8. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations
    9. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    10. Vitamin D Receptor, UVR, and Skin Cancer: A Potential Protective Mechanism Journal of Investigative Dermatology · 2008 · 51 citations
    11. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 37 citations
    12. Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor 2007 · 36 citations
    13. The 1,25-dihydroxyvitamin D3-independent actions of the vitamin D receptor in skin 2010 · 18 citations
    14. Ligand‐Independent Actions of the Vitamin D Receptor: More Questions Than Answers JBMR plus · 2021 · 11 citations
    15. The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding Receptors · 2024
    16. Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia in four Egyptian families: report of three novel mutations in the vitamin D receptor gene Journal of Pediatric Endocrinology and Metabolism · 2014 · 10 citations
    17. Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice Journal of Investigative Dermatology · 2011 · 100 citations
    18. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    19. The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment 2008 · 25 citations
    20. Mediator1: An Important Intermediary of Vitamin D Receptor–Regulated Epidermal Function and Hair Follicle Biology Journal of Investigative Dermatology · 2012 · 5 citations
    21. Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention Nutrition reviews · 2008 · 271 citations
    22. Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands Journal of bone and mineral research · 2007 · 137 citations
    23. Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets due to a Mutation Causing Multiple Defects in Vitamin D Receptor Function Endocrinology · 2004 · 67 citations
    24. Molecular docking of Vitamin D3 Receptor (VDR) with potential herbal substance as ligand to prevent excessive hair loss in menopausal women Indonesian Journal of Medical Chemistry and Bioinformatics · 2022
    25. Physiological Insights from the Vitamin D Receptor Knockout Mouse Calcified Tissue International · 2012 · 34 citations
    26. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    27. Vitamin D and the skin: Focus on a complex relationship: A review Journal of Advanced Research · 2014 · 139 citations
    28. Does D matter? The role of vitamin D in hair disorders and hair follicle cycling Dermatology Online Journal · 2010 · 98 citations
    29. Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle British Journal of Dermatology · 2006 · 95 citations
    30. Analysis of 1,25-Dihydroxyvitamin D3 Receptors (VDR. in Basal Cell Carcinomas ˜The œAmerican journal of pathology · 1999 · 42 citations