May 2025 in “Journal of Ayurveda and Integrated Medical Sciences” In this phase 3 clinical trial, participants taking Vedistry Amla + Tablets for hair concerns experienced significant reductions in hair fall and improvements in hair texture, strength, and scalp health over three months, with stable laboratory parameters and increased Vitamin D and antioxidant levels.
2 citations
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August 2022 in “Clinical Case Reports” This case report describes a 17-year-old girl with telogen effluvium and severe hair loss following a suspected COVID-19 infection and a history of similar episodes since childhood.
September 2024 in “Polish Journal of Public Health” The researchers reported finding 53 therapeutic and skincare products for hirsutism and hypertrichosis in Polish pharmacies and drugstores, identifying dienogest and cyproterone acetate as common active ingredients for hirsutism. They noted promising new treatments include eflornithine, acyclovir, licorice, and vitamin D.
47 citations
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September 2023 in “Pharmacological Reports” In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.
37 citations
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April 2011 in “Journal of Biological Chemistry” This study discovered a novel interaction between the vitamin D receptor and LEF1, essential for normal Wnt signaling in keratinocytes, which is crucial for regular hair cycling.
January 2024 in “Fitoterapia” In this study, the analysis of Ukraine's pharmaceutical market from 2020 to 2023 found a large variety of Vitamin D3 preparations, predominantly domestic and synthetic, with capsule forms being common; consumer surveys highlighted that doctor recommendations strongly influenced purchasing decisions.
1308 citations
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March 1998 in “Journal of bone and mineral research” This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
82 citations
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April 1981 in “Clinical endocrinology” This study describes a case of vitamin D resistant rickets in a young girl due to end organ unresponsiveness, highlighting a possible new subtype of the disorder with distinct clinical features.
50 citations
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October 1986 in “European journal of pediatrics” This case study reported that absence of alopecia does not reliably predict responsiveness to vitamin D treatment in Vitamin D-dependent rickets type II, as demonstrated by a patient with normal hair growth who showed extreme resistance.
36 citations
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January 2017 in “Journal of Obstetrics and Gynaecology Research” This review discusses the association between vitamin D receptor polymorphisms and polycystic ovary syndrome, noting the need for further research on their impact on the disorder's manifestations.
7 citations
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October 2019 in “Clinical, Cosmetic and Investigational Dermatology” This study found that specific polymorphisms in the VDR gene, Taq1, and Cdx1, were significantly associated with increased risk of chronic telogen effluvium in women.
6 citations
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January 2020 in “Postepy Dermatologii I Alergologii” This article recommends assessing serum ferritin and vitamin D levels in patients with diffuse hair loss before starting treatment, but it reports no new clinical results.
5 citations
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June 2021 in “Pharmacological Reports” This study suggests that vitamin D treatment may be less effective in reducing thyroid autoimmunity for euthyroid men with early-onset androgenic alopecia compared to other men with autoimmune thyroiditis.
1 citations
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January 2009 in “Trepo - Institutional Repository of Tampere University” This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.
1 citations
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January 2024 in “Pediatric Endocrinology Diabetes and Metabolism” In this retrospective study of eight Saudi children with hereditary vitamin D resistant rickets, researchers observed that adjunctive cinacalcet appeared safe and showed initial promise in improving serum PTH levels, though further investigation is needed to confirm its efficacy.
This study found a significant association between lower vitamin D levels and increased severity of androgenetic alopecia in men.
January 2020 in “Journal of quality in health care & economics” This study found that all participating depressed women in the sample had vitamin D deficiency or insufficiency, suggesting a possible association between vitamin D levels and depression among women in Iraq.
78 citations
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November 2005 in “Endocrinology” This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.
6 citations
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November 2021 in “Oncology Research and Treatment” This study found that lower expression of VDR protein in breast cancer patients is associated with increased bone metastasis and poorer prognosis, making it a significant prognostic factor.
March 2026 in “Nutrients” This study found that adequate vitamin D status is necessary for metformin to effectively reduce prolactin levels in men with iatrogenic hyperprolactinemia, while improvements in glycemic control were observed across all vitamin D groups.
6 citations
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June 2018 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” In this study, eight patients with hereditary vitamin D-resistant rickets who share a specific VDR mutation showed improved clinical symptoms except alopecia after up to 11 years of treatment.
17 citations
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July 2015 in “Biomolecules and Biomedicine” This study found that women with PCOS had higher levels of Nesfatin-1 and lower levels of vitamin D, which may be linked to increased blood pressure and potential hypertension.
10 citations
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May 2017 in “PLOS ONE” This study found that serum 25-hydroxyvitamin D was inversely associated with serum ferritin levels in Korean men, positively associated in premenopausal women, and not associated in postmenopausal women.
7 citations
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January 2017 in “Journal of Clinical Biochemistry and Nutrition” This study found that vitamin D was positively associated with serum ferritin levels in Korean women without metabolic syndrome, but this association was not observed in those with metabolic syndrome.
6 citations
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March 2023 in “Journal of Cosmetic Dermatology” In this study, alopecia areata and vitiligo patients had significantly lower serum BDNF and vitamin D levels, which were inversely associated with depression and quality of life, suggesting a potential combined role in the development of depression.
3 citations
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January 2020 in “Indian Journal of Dermatology” This study found that certain VDR gene polymorphisms are more prevalent in female pattern hair loss patients than in healthy controls, suggesting these polymorphisms may increase disease risk.
2 citations
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May 2022 in “Diagnostics” This study confirmed that 25(OH)D3 can be detected in hair samples from healthy young adults, but no correlation was found between hair and serum 25(OH)D3 concentrations, indicating limited potential as a standalone biomarker.
1 citations
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December 2018 in “Indian journal of paediatric dermatology” This study found that children with alopecia areata had significantly lower serum vitamin D levels than healthy controls.
October 2025 in “Medical Journal of Babylon” In this study, researchers found that female COVID-19 patients experiencing hair loss had higher testosterone levels and lower Vitamin D levels than healthy controls, suggesting these hormonal factors may play a role in post-COVID-19 hair loss.
January 2025 in “Egyptian Journal of Dermatology and Venerology” This study found that COVID-19 vaccination initially lowered vitamin D levels in serum and hair but increased serum levels after the second dose, except for the Pfizer group. Hair vitamin D showed a nonsignificant increase, and hair loss was most common with the AstraZeneca vaccine.