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Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study aims to understand various diseases in older adults.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Doctors need to be better prepared to assess and treat obesity in patients.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.