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Adding a second method to PROTACs could improve cancer treatment.

The document discusses various eye conditions and their treatments, including a rare eye cancer in a baby, vision loss from a cancer drug, cataracts from a baldness treatment, a rare skin disorder, and a specific type of eye disease diagnosed with a special imaging technique.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

The KRTAP21-1 gene affects wool yield and can help improve wool production.

Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.

Tiger cubs fed artificial milk lacking certain amino acids developed eye problems and hair loss.

Hair analysis shows infants and mothers in north-western Spain are exposed to environmental pollutants, with factors like diet and residence affecting pollutant levels.

Some skin diseases and their treatments can negatively affect male fertility.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.

SHBG may be a useful early indicator and treatment target for PCOS.

Three siblings with a genetic form of rickets showed different symptoms of the disease.

Kolaviron and quercetin may help treat prostate issues.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.

Finasteride may lower cholesterol and slow heart disease progression.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.

HIV-positive pregnant women are more likely to experience severe bleeding, and a pregnant woman with familial hypertriglyceridemia had a successful early delivery with special care.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.