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Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

We need better ways to test and understand SARMs to make safer and more effective treatments.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

SOX9 is essential for the development of various organs and hair follicles.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Too much androgen can cause hair loss; finasteride may help.

Finasteride may cause long-lasting sexual side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Some herbs show promise as antiandrogenic agents.

Finasteride doesn't affect bone density in male rats.

Finasteride causes lasting fertility decrease in rats.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.