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Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

Captopril reduces heart mass, while minoxidil has opposite effects and side effects.

Genetic variations affecting skin structure play a key role in severe acne.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Blocking a specific protein signal can make hair grow on mouse nipples.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Prolactin may be important for skin growth and immune function.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.