1 citations
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May 1987 in “The Lancet” Topical minoxidil may help hair growth by improving blood flow to hair follicles.
25 citations
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November 1987 in “British Journal of Dermatology” This study observed increases in scalp blood flow following the application of 3% minoxidil and 0.1% hexyl nicotinate in individuals with alopecia.
October 2022 in “Journal of ophthalmology” This review discusses the implementation and mechanisms of photobiomodulation therapy in various medical fields, including ophthalmology, and reports no new clinical results.
January 2022 in “Revista Saúde em Foco” This review suggests that combining microneedling with growth factors may significantly stimulate eyebrow growth by promoting new hair follicle formation and improving cellular processes.
This study found that tadalafil use was associated with a decreased risk of major adverse cardiac events and venous thromboembolism in men with lower urinary tract symptoms.
14 citations
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April 1987 in “PubMed” In an open trial, 2.8% minoxidil solution applied topically stimulated new hair growth in 45% of male patients with male pattern alopecia, though patient self-assessments were more favorable than objective evaluations.
This case report suggests that Minoxidil may be a potential cause of central serous chorioretinopathy in a 39-year-old cardiologist using it for androgenic alopecia.
In this case report, the authors detail a successful management of early scalp ischemia after hair transplantation using the FLOW protocol, which emphasizes cause correction, local vasodilation, oxygenation optimization, and wound care, resulting in recovery without necrosis.
10 citations
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August 2023 in “Advanced Science” This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.
March 2024 in “Journal of integral sciences” This review highlights the interest in rosemary oil as a natural remedy for hair growth, contrasting its bioactive components and antioxidant properties with minoxidil's vasodilating mechanism, but notes that comprehensive clinical comparisons of their long-term efficacy and safety are still lacking.
February 2023 in “riUfes (Universidade Federal do Espírito Santo)” This study found that supraphysiological doses of testosterone alter endothelial relaxation pathways in hypertensive rats, with varied contributions from nitric oxide, prostanoids, and endothelium-derived hyperpolarizing factors, influenced by estrogen and dihydrotestosterone levels.
In this study, Minoxidil and other treatments prevented alopecia in mice induced by Paclitaxel, with quantitative data supporting the inhibition of hair loss.
This review examines the roles of adenosine and caffeine in regulating hair growth cycles but reports no new results, highlighting unanswered questions about their specific mechanisms.
February 2026 in “Journal of Drugs in Dermatology” This systematic review discusses various topical, oral, injectable, and non-pharmacological treatments for androgenetic alopecia, examining both current and emerging therapeutic options in addressing this common form of hair loss.
March 2025 in “Frontiers in Cell and Developmental Biology” This study reviewed how neuropeptides and cutaneous innervation play crucial roles in the process of wound healing, suggesting they significantly influence inflammation and tissue repair phases.
September 2024 in “Health Sciences” This review discusses treatments for androgenic alopecia, including minoxidil, finasteride, and hormonal therapies with antiandrogens, and reports no new clinical findings.
63 citations
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January 1984 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth by increasing cell division and DNA synthesis.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” This study found that Minoxidil had biphasic effects on normal human keratinocytes, stimulating proliferation at micromolar doses, but showing antiproliferative, pro-differentiative, and cytotoxic effects at millimolar concentrations.
21 citations
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April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
16 citations
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October 2018 in “Biochemical and Biophysical Research Communications” In this study, sildenafil was found to enhance human dermal papilla cell proliferation and promote hair growth in mice, suggesting potential use in alopecia treatment.
10 citations
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April 2019 in “Journal of Analytical Science and Technology” In this study, hydrolysates of lactic acid bacteria were found to enhance hair growth in C57BL/6 male mice more effectively than 5% minoxidil.
45 citations
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October 1988 in “British Journal of Clinical Pharmacology” This study found that topical minoxidil increased heart rate and had significant effects on cardiac volumes and mass compared to placebo, but its long-term safety remains uncertain.
25 citations
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December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
2 citations
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December 2019 in “Biomedical dermatology” In this study, researchers found that topical ketoconazole showed delayed hair growth compared to minoxidil in female pattern hair loss but had fewer side effects, though patient satisfaction was similar for both treatments.
149 citations
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March 2004 in “Journal of Dermatological Science” This study found that minoxidil stimulates hair follicle growth by promoting dermal papilla cell survival and activating ERK and Akt pathways, which leads to increased proliferation and reduced cell death.
34 citations
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January 1977 in “American Journal of Cardiology”
21 citations
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January 2019 in “Lasers in Medical Science” This review found that low-level laser therapy significantly increased hair density in adults with androgenic alopecia compared to sham treatments, with greater effects observed at lower treatment frequencies.
12 citations
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March 2014 in “ISRN Pharmacology (Print)” This study demonstrated that Ketoconazole, Minoxidil, and Minoxidil with Tretinoin all significantly stimulated hair growth in mice, with Minoxidil alone showing the most effectiveness.
11 citations
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June 2020 in “Dermatologic Therapy” This study suggests that combination therapies including minoxidil with either finasteride, low-level laser light therapy, or microneedling are more effective than minoxidil alone for treating androgenetic alopecia.
11 citations
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May 1990 in “Journal of Dermatological Science” In this animal study, topical diazoxide treatment led to increased hair thickness and follicle growth in bald stumptailed macaques without causing notable systemic side effects.