64 citations
,
January 1998 in “Drugs” In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.
25 citations
,
June 2017 in “Molecular and Cellular Endocrinology” This review discusses the negative effects of anabolic androgenic steroids on various organ systems in men and reports no new results, highlighting the need for physician awareness.
8 citations
,
January 1996 in “Gynecological Endocrinology” This review evaluates therapies for hyperandrogenism, highlighting cyproterone acetate as the preferred treatment due to its potency and tolerability in managing symptoms in women.
6 citations
,
March 2012 in “Journal of the European Academy of Dermatology and Venereology” This study found that 12 cycles of chlormadinone acetate in hormonal contraceptives significantly improved oily skin and hair quality, enhancing psychosocial well-being in healthy women.
2 citations
,
January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This review discusses therapeutic principles for managing hirsutism and androgenetic alopecia during the menopausal transition and peri-/postmenopause but reports no new clinical results.
June 2026 in “Frontiers in Oncology” In this study, researchers analyzed adverse event reports from the FAERS database to identify safety concerns associated with ipilimumab in elderly patients, noting common issues like gastrointestinal events and new signals such as orchitis and alopecia areata, with timing influenced by body weight.
359 citations
,
September 2017 in “European Journal of Epidemiology” This article discusses the rationale, design, and significant findings of the long-running Rotterdam Study but reports no new clinical results.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
336 citations
,
August 2015 in “European Journal of Epidemiology” This article reviews the design and objectives of the Rotterdam Study, as well as summarizes major findings, without reporting new results.
266 citations
,
November 2013 in “European Journal of Epidemiology” This article outlines the rationale and design of the Rotterdam Study, summarizes its major findings, and updates its objectives and methods; it reports no new research results.
247 citations
,
August 2011 in “European Journal of Epidemiology” This article outlines the rationale, design, major findings, and updated objectives of the ongoing Rotterdam Study, without presenting new research data.
219 citations
,
September 2009 in “European journal of epidemiology” This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.
178 citations
,
August 2016 in “Advances in wound care” This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
152 citations
,
April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
151 citations
,
May 2014 in “American Journal of Clinical Dermatology” This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
128 citations
,
January 1996 in “Journal of analytical toxicology.” This study suggests that while hair analysis using GC-MS is a sensitive method for detecting cocaine ingestion, it may not reliably indicate the amount, timing, or duration of drug use due to interindividual variability and multiple incorporation mechanisms.
125 citations
,
September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
112 citations
,
January 2014 in “Molecular and cellular therapies” This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.
98 citations
,
May 2008 in “British Journal of Dermatology” This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
83 citations
,
January 2015 in “World Journal of Stem Cells” This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.
69 citations
,
January 2020 in “Veterinary World” This review examines factors influencing dermatophyte infection in companion animals, focusing on prevalence, clinical signs, pathogenesis, immune response, and the impact of cortisol and cytokines, but reports no new clinical results.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
61 citations
,
January 2019 in “American Journal of Clinical Dermatology” This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.
59 citations
,
September 2008 in “Journal of Burn Care & Research” This study found that a new topical nitric oxide gel significantly accelerated burn wound healing in mice by enhancing re-epithelialization, hair follicle regeneration, collagen deposition, and angiogenesis compared to controls.
58 citations
,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that patients with post-finasteride syndrome exhibited major depressive disorder, severe erectile dysfunction, and neuropathy, alongside altered neuroactive steroid levels in cerebrospinal fluid.
52 citations
,
October 2010 in “Antiviral Therapy” This review discusses recent advances in monophosphate prodrug strategies for HCV drug discovery, aiming to enhance oral absorption and stability, and reports no new clinical results.
49 citations
,
July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
47 citations
,
September 2015 in “Journal of Drug Delivery Science and Technology” This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.
47 citations
,
October 2014 in “Expert Opinion on Emerging Drugs” This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.