research Role of 5α-Reductase Inhibitors in Benign Prostatic Diseases
5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.
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research Identification of a Novel Homozygous LAMB3 Mutation in a Chinese Male With Junctional Epidermolysis Bullosa and Severe Urethra Stenosis: A Case Report
A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Economic Analysis of Finasteride: A Model-Based Approach Using Data from the Proscar Long-Term Efficacy and Safety Study
Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Arecaceae
Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
research Clinical Significance of Intravesical Prostatic Protrusion/Prostate Volume
The IPP index is linked to storage symptoms and leftover urine, and may help manage urinary tract symptoms.
research Benign Prostatic Hyperplasia, Metabolic Syndrome, and Androgenic Alopecia: Is There a Possible Relationship?
People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.
research Synthesis and Study of Some 17a-Aza-D-Homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Dissociative Disorders in Childhood Sexual Abuse Victims
Passiflora incarnata may help with anxiety but has risks and drug interactions.
There's a genetic link between Fragile X Syndrome and Autism Spectrum Disorder.
6.7% of urine cultures showed hospital-acquired urinary tract infections.
Children used screens more during COVID-19, causing various health complaints.
Autism Spectrum Disorder is often underdiagnosed in females.
Dissociative disorders in childhood sexual abuse victims are more common in males.
Most pregnant teenagers are not dissatisfied with their body image but worry about weight.
Diagnosing tuberculosis after knee surgery is challenging due to non-specific symptoms.
Post-COVID-19 syndrome is more common in older, severely affected patients.
Psychiatrists should be part of pain management teams due to the psychological aspects of pain.
research This Month in Adult Urology
The document highlights recent findings and treatments in urology, including prostate cancer diagnostics, urinary incontinence, and new therapies.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Partial Biotinidase Deficiency: Clinical and Biochemical Features
Children with partial biotinidase deficiency are healthy at birth but may develop symptoms that improve with biotin therapy.
research The Evaluation of the Role of Androgens in Hirsutism and the Use of a New Anti-Androgen Cyproterone Acetate for Therapy
Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
research Biotin Deficiency Complicating Parenteral Alimentation: Diagnosis, Metabolic Repercussions, and Treatment
Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.
research Hair Loss, Insulin Resistance, and Heredity in Middle-Aged Women: A Population-Based Study
Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome
Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
research Familial and Sporadic Porphyria Cutanea Tarda
Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia
Early hair loss may indicate prostate issues.
research The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis
Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
research Fluoride Exposure and Pubertal Development in Children Living in Mexico City
Higher fluoride levels may delay puberty in boys.
research Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials
Baricitinib improved severe hair loss in adults over 52 weeks and was safe to use.
research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-Positive Breast Cancer on Adjuvant Aromatase Inhibitor Therapy: Meta-Analysis
Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.
research The Risk of Dementia with the Use of 5 Alpha Reductase Inhibitors
Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.
research Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study
Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.
research An Old Problem with a New Cause: 5 Alpha Reductase Inhibitors and Persistent Sexual Dysfunction
Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
research Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year
Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.