Dutasteride vs Finasteride: Assessment of Differences in Acute Urinary Retention Rates and Surgical Risk Outcomes in an Elderly Population Aged 65 Years and Older

    May 2008 in “ PubMed
    Thomas C Fenter, Earl E. Davis, Manan Shah, Pei-Jung Lin
    TLDR Dutasteride is more effective than finasteride in reducing urinary retention and surgery risks in people aged 65 and older.
    This study compared the effects of dutasteride and finasteride on acute urinary retention (AUR) and prostate-related surgeries in patients aged 65 and older. Analyzing data from 5,090 patients over a year, it was found that those treated with dutasteride had a lower rate of AUR (12%) compared to those on finasteride (14.7%), with an odds ratio of 0.79. Additionally, the risk of prostate-related surgeries was lower for dutasteride patients (3.9% vs 5.1%), with an odds ratio of 0.77. The study concluded that dutasteride was more effective in reducing AUR and surgical risks than finasteride in this population.
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