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Adalimumab is the most effective treatment for severe hidradenitis suppurativa, but more research is needed to improve treatment options.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

Antioxidants can help improve hair growth in people with alopecia areata.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

SLE and DM can coexist but are rare and need careful evaluation.

Nearly half of the classification tools in the National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries might not effectively guide management for general practitioners.

Janus kinase inhibitors are effective and generally safe for treating hair loss in adults with alopecia areata.

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

Genetic testing confirmed a rare skin disorder in a young girl, which improved with zinc supplementation.

Hirsutism in teens is often due to polycystic ovarian syndrome and needs careful assessment and support.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Ayurvedic treatment improved hypothyroidism in a 30-year-old man.

A spayed dog with vaginal bone structures causing infection was successfully treated by removing the bones and administering medication.

Rice water and hibiscus can help improve hair health and growth.

When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.

Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Biofield Energy Healing significantly increased hair growth by making hair root cells grow more.

Biofield Energy Healing may increase hair growth by enhancing cell proliferation.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Autonomic dysfunction is common in hypertensives but may not cause diastolic dysfunction in resistant hypertension.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.