January 2004 in “Laboratory Animal Science and Administration” This study found that the hairless mutant gene in C 57BL/6 mice affects the hair follicle cycle and leads to early thymus degeneration and distinct skin changes.
32 citations
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November 2004 in “Journal of pharmaceutical sciences” This study quantifies the follicular uptake of tea tree oil in bovine udder skin, with microemulsion showing the highest concentration among different formulations tested.
December 2022 in “Biochemical and Biophysical Research Communications” This study found that HtrA2 inactivation in mnd2 mice is associated with delayed hair cycle phases and growth retardation of adipocytes, suggesting HtrA2's role in regulating adipogenesis-related hair growth.
April 2023 in “Journal of Investigative Dermatology” This study suggests that histological features of primary melanoma can partially predict lymph node metastasis using AI, achieving a best prediction AUROC of 0.65.
71 citations
,
March 2016 in “PubMed” This study found that sub-100 nm solid lipid nanoparticles showed the most effective skin penetration and depth, primarily via hair follicles, in rat skin evaluations.
January 1996 in “Lasers in Surgery and Medicine” This letter to the editor by Walter P. Unger discusses topics related to hair transplantation and reports no new research findings.
1 citations
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November 2022 in “Pharmaceutical research” In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.
10 citations
,
December 1999 in “Journal of The American Academy of Dermatology” This case report describes how a combined nude and hair-bearing full-thickness skin graft was used after micrographic surgery to achieve a cosmetically satisfactory reconstruction of a large eyebrow defect.
February 2026 in “American Journal of Clinical Dermatology” This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.
57 citations
,
December 2012 in “Journal of Biomedical Optics” This review discusses the application of confocal laser scanning microscopy for studying nanoparticle interactions with skin and highlights its potential for broad applications, but reports no new experimental findings.
10 citations
,
August 2015 in “Journal of biophotonics” This study found that applying benzyl nicotinate on open hair follicles led to a significant increase in blood flow, highlighting the role of the follicular pathway in epidermal penetration.
January 2018 in “Springer eBooks” Different races and genders have unique skin and hair issues, requiring specialized care and more research for effective treatment.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
December 2025 in “Pakistan Journal of Health Sciences” This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.
January 2016 in “Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver” This study found that novel biodegradable nanocarriers with highly hydrophobic cores significantly increased the solubility and sustained release of hydrophobic drugs and dyes, showing promise for drug delivery applications.
5 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” A woman had 13 non-cancerous cysts on her scalp successfully removed in one surgery.
6 citations
,
January 2013 in “Urology” This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
15 citations
,
February 2014 in “BMC Research Notes” This study found that male androgenic alopecia patients using the X5 hair laser device showed a statistically significant increase in hair growth over a 26-week period.
4 citations
,
July 2012 in “Genesis” This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.
December 2019 in “Reproduction Fertility and Development” This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.
16 citations
,
September 2018 in “Journal of Molecular Liquids” This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.
This study observed that long-term laser hair removal in women may alter hair follicle structures and stem cell interactions, with dermal fibrosis potentially influencing hair regrowth prevention.
7 citations
,
October 2024 in “Cells” The researchers reported that autophagy, a lysosome-dependent degradation mechanism, plays a significant role in the cellular remodeling of keratinocyte differentiation in the skin, affecting the properties of the differentiation products by altering cellular components during this process.
82 citations
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May 2005 in “Dermatologic therapy” This review highlights advancements in hair laser removal technologies, which achieve approximately 75% hair reduction in light-skinned individuals, noting the long-pulsed Nd:YAG laser as safest for dark-skinned patients, but reports no new results.
November 2021 in “Clinical, cosmetic and investigational dermatology” This case report details an 80-year-old woman with circle hair potentially linked to acquired ichthyosis from multiple myeloma, where a prescribed topical treatment led to clinical improvement.
This study observed that liposomes encapsulating minoxidil and PEP penetrate the skin at a slower rate but may reach deeper layers compared to a foam formulation.
2 citations
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May 2021 in “Research Square (Research Square)” This study found that ketoconazole-loaded solid lipid nanoparticles significantly improved skin permeation and retention compared to a drug suspension and marketed product, demonstrating enhanced delivery into deeper skin layers.
58 citations
,
April 2009 in “Current stem cell research & therapy” This review discusses the differentiation and reprogramming capabilities of both hematopoietic and non-hematopoietic stem cells and their significance for regenerative medicine; it reports no new experimental results.
24 citations
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November 2021 in “PLoS ONE” In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.
February 2026 in “International Journal of Basic & Clinical Pharmacology” This study found that hair rejuvenation therapies and patient comorbidities, such as diabetes mellitus, were significantly associated with adverse drug reactions in cosmetic treatment recipients.