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Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

No treatment fully prevents hair loss from chemotherapy yet.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Growth factors are crucial for hair development and could help treat hair diseases.

Wool follicles are complex, involving interactions between different cell types and structures.