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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride helps induce ovulation in nonresponder PCOS women.

Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.

Testosterone's effects on COVID-19 are unclear and need more research.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

People with hypohidrotic ectodermal dysplasia are more likely to experience long-term fatigue and hair loss after COVID-19.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Anabolic steroid users may face higher risk of severe COVID-19.

Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.

COVID-19 infection can significantly cause temporary hair loss.

Platelet-Rich Plasma therapy helps increase hair density and regrowth for some types of hair loss.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

ADAM17 could be a potential target for treating PCOS.

Certain genetic differences may affect how likely someone is to get COVID-19 and how severe it might be.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Insulin resistance linked to obesity may increase COVID-19 severity.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.