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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Finasteride reduces hair growth and is safe for women with excessive hair.

Rats had lasting erectile problems after stopping a certain medication.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Eclipta alba extract could be a promising natural treatment for hair loss.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Certain Dibenzo derivatives may help treat prostate cancer.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.