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Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Both drugs lower DHT levels, with GI198745 being more effective.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

New hybrid compound found to effectively prevent hair loss.

Finasteride reduces movement issues in Parkinson's disease rats.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Minoxidil boosts enzymes that help hair growth.

Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Dutasteride may help shrink prostate cancer tumors.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.

Created microspheres show potential for safe and effective use in prostate artery embolization.

Using a laser helmet with Minoxidil works better for male hair loss than Minoxidil alone, with no extra side effects.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.