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Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

The review suggests there's no agreed treatment for Frontal Fibrosing Alopecia, but hydroxychloroquine and 5a-reductase inhibitors are most effective. New treatments like platelet-rich plasma and LED light could help if standard treatments fail.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Plant extracts may help treat hormone-related hair loss.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Rice bran extract might help prevent hair loss.

New tests detect finasteride and dutasteride in urine quickly and easily.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Certain drugs change freshwater snail shells to a "banana" shape.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.