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Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Compounds from the plant Mammea siamensis may help treat hair loss.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Eclipta alba extract could be a promising natural treatment for hair loss.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Effective treatment guidelines for frontal fibrosing alopecia are still unclear.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.