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Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Chaga mushrooms contain compounds that may promote hair growth better than common treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Eclipta alba extract could be a promising natural treatment for hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Effective treatment guidelines for frontal fibrosing alopecia are still unclear.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The study created a new method to test drugs that affect hormone processing in skin.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.