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NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Overexpression of HDGF in melanocytes does not cause cancer.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

PCAT1 helps hair growth by controlling miR-329/Wnt10b.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

SOX4 is crucial for the development of melanoma.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.

High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Targeting and modifying the stem cell niche can improve regenerative therapies.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.