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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

No treatment fully prevents hair loss from chemotherapy yet.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Nanoparticle systems make cancer treatment less toxic.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.