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In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.

This study found that high doses of ethyl acetate extract from Tridax procumbens can have specific toxic effects in rats, including organ damage and significant changes in some serum biochemical parameters.

This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.

This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.

This study found that quercitrin, a natural compound, enhances Wnt/β-catenin signaling and may help mitigate synapse loss and memory impairment in Alzheimer's models.

This study found that forsythoside A, a compound from Forsythia suspensa, may counteract DHT-induced hair regrowth inhibition by selectively inhibiting TRPV3 channels.

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.

This case report describes two patients with trichothiodystrophy who exhibited a different pattern of hair protein composition changes, suggesting a subgroup of TTD characterized by partial loss of high-sulfur proteins without significant alteration in their amino acid composition.

This study found that compound 4 from Urtica triangularis subsp. pinnatifida exhibited stronger anti-BPH activity against BPH-1 cells with an IC50 of 79.75 μM compared to finasteride's IC50 of 91.8 μM, while compounds 1, 2, and 5 showed moderate activity.

This case report details two siblings with trichothiodystrophy, identifying reduced hair sulfur content as essential for diagnosis despite varied symptoms complicating recognition.

This study found that Carthamus tinctorius floret ethanolic extract stimulated melanogenesis in B16F10 murine melanoma cells without cytotoxicity, suggesting its potential as a treatment for gray hair.

This study proposes that combining trazodone and clomiphene citrate could potentially restore libido synaptic circuits and treat post-finasteride syndrome, which involves persistent sexual dysfunction after discontinuing finasteride treatment.

This study identified that rose, thyme geraniol, palmarosa, and tolu balsam essential oils activate TRPV1, with citronellol and geraniol as newly recognized agonists.

In this study, researchers reviewed current treatments for trichotillomania and found that psychotherapy, particularly cognitive-behavioral therapy like habit reversal training, is most effective, with some medications helping to alleviate symptoms, though further study is needed on their use.

In this study, Trichophyton tonsurans and Microsporum canis were identified as the primary causes of tinea capitis, with terbinafine treatment showing the highest cure rate. Non-commercial kits surpassed real-time PCR commercial kits in specificity and sensitivity for diagnosis.

In this animal study, treatment with Trachyspermum copticum seed extract significantly altered IL-1 and KGF/FGF-7 gene expression, improving dermatitis and hair growth in mice compared to controls and corticosteroids.

This study found that camphor and similar compounds depress neural activity in rat mechanoreceptors, suggesting that their effects may not be mediated through TRP channels.

This study found that povidone iodine, thiabendazole ointment, captan ointment, and Burroughs Wellcome Ringworm Ointment were effective against Trichophyton equinum var. autotrophicum in horses, but large-scale use may be limited by practicality and cost.

TRPM5 is crucial for maintaining hair growth.

This study highlights the underexplored allergenic potential of Trichophyton rubrum, a dermatophyte, which can trigger IgE-mediated allergic reactions and a Th2 immune response shift, underscoring the need for its inclusion in diagnostic panels and further research for treating chronic mycoses and related allergies.

This review discusses treatment options for trichotillomania, focusing on cognitive-behavioral interventions and promising developments in combined pharmacotherapy and therapy approaches, but reports no new findings.

This case report describes an 18-year-old male with kerion celsi from Trichophyton tonsurans infection whose condition improved with terbinafine treatment, and highlights that although IL-17A expression increased in skin lesions, it was associated with disrupted antimicrobial peptide expression and severe inflammation, causing tissue damage.

This study systematically reviewed clinical findings in trichothiodystrophy patients and suggested a new clinico-genetic classification to help better understand the ichthyotic phenotype and its management.

This study surveyed dermatologists and found that Doxepin was the most preferred anti-depressant for treating psycho dermatoses in elderly patients.

This article reviews the genetic and phenotypic characteristics of Trichothiodystrophy and discusses the associated DNA repair defects, but does not report new clinical findings.

Dithranol reduces inflammation in alopecia areata by lowering certain immune responses.

This study found that human hair shows more susceptibility to perforation by Trichophyton mentagrophytes and Trichophyton verrucosum compared to animal hair, with black human hair serving as a reliable diagnostic tool for differentiation between the two species.