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Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

SHBG may be a useful early indicator and treatment target for PCOS.

Hydrogels could lead to better treatments for wound healing without scars.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Melatonin improved mental health and metabolism in women with PCOS.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Melatonin may help treat PCOS symptoms in rats.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.