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Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Malnutrition severely harms growth and development in young baboons.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Flutamide reduces hair growth better but has more side effects.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Melatonin improved mental health and metabolism in women with PCOS.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

The document concludes that proper diagnosis and treatment of common scalp disorders are important for both physical and psychological health.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Etretinate has only moderate effects on localized scleroderma and lichen sclerosus.

Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Finasteride reduces hair growth and is safe for women with excessive hair.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.