2 citations
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October 2001 in “Analytical Sciences” A new compound that could treat various androgen-related conditions was created and analyzed.
11 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that among the tested analogs, compound 4e was the most effective in inhibiting wax esters in vivo in the Golden Syrian hamster ear model.
6 citations
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September 2015 in “Journal of Medicinal Chemistry” This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.
20 citations
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January 2003 in “Chemical and Pharmaceutical Bulletin” This study reports that five new progesterone derivatives demonstrated inhibitory activity against the 5α-reductase enzyme and binding affinity for the androgen receptor in an in vitro hamster model.
January 2015 in “International Journal of Pharma and Bio Sciences” This review discusses the traditional medicinal uses of Tridax procumbens, attributing its therapeutic properties to various active phytochemicals, but reports no new clinical findings.
5 citations
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February 1997 in “Bioorganic & Medicinal Chemistry” This study found that among 17 beta-(N-ureylene-N,N'-disubstituted)-4-azasteroids, those with an N'-phenyl moiety were the most effective inhibitors of human type I 5 alpha-reductase.
8 citations
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January 2013 in “Medicinal chemistry” This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.
2 citations
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April 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” This article discusses the preparation of tritium-labeled testosterone metabolites and reports no new experimental findings.
January 2022 in “Asian journal of Current Research in Clinical Cancer” This study reviews the potential of dibenzo derivatives as safer cancer treatments but finds conflicting evidence about their effectiveness, possibly due to structural differences among the compounds, and reports no new results.
4 citations
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March 2018 in “Journal of labelled compounds & radiopharmaceuticals” In this study, researchers developed a new prostate cancer imaging agent, a [99m Tc]tricarbonyl complex derived from finasteride, which demonstrated high radiochemical purity and significant uptake in the prostate of a rat model, suggesting its potential for noninvasive prostate cancer imaging.
January 2024 in “Revista del Centro Dermatológico Pascua” In this case report, a 24-year-old male with acquired distal trichorrhexis nodosa showed significant improvement after avoiding harmful hair treatments and using a repair shampoo alongside biotin and zinc supplements.
58 citations
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December 2021 in “Phytomedicine Plus” This review article compiles past and updated information on Tridax procumbens' traditional uses and chemical compounds, highlighting its diverse pharmacological activities such as wound healing, but emphasizes the need for further toxicological research.
December 2023 in “Reactions weekly” December 2023 in “Reactions weekly” September 2013 in “Reactions weekly” July 2014 in “Americanae (AECID Library)” This study found that extracts from Tridax procumbens and Ouratea spectabilis reduced seed germination and inhibited root and hypocotyl growth in lettuce, indicating potential allelopathic effects.
6 citations
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July 2015 in “International Journal of Dermatology” This study observed that multiple familial trichoepitheliomas commonly presented with a cribriform histopathological tumor pattern, differentiating them from solitary trichoepitheliomas.
400 citations
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January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.
1 citations
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December 1970 in “European journal of endocrinology” This study reports experience treating 140 women with hirsutism and other virilism signs using cyproterone acetate and ethinyl estradiol, focusing on those treated for over five months.
17 citations
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August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
This study found that premenopausal exercising women with oligomenorrhea had lower triiodothyronine levels and truncal fat percentage compared to other groups, suggesting distinct energetic and reproductive profiles.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that hydroxycinnamate derivatives, especially a compound named 10a, effectively inhibited SRD5A1 activity and protein expression in cell assays, suggesting potential for treating androgen-related conditions.
23 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” This study found that several synthesized pregnane derivatives exhibited significant inhibitory effects on testosterone conversion to dihydrotestosterone and reduced related androgenic parameters in multiple pharmacological models.
1 citations
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March 2013 in “The European Journal of Contraception & Reproductive Health Care” This publication discusses the political rationale behind the French regulator ANSM's decision to withdraw Diane®-35 from the market, in response to health concerns associated with third-generation oral contraceptives.
February 2023 in “Reactions Weekly” 18 citations
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September 1979 in “DMW - Deutsche Medizinische Wochenschrift” In this study, Diane was reported to effectively treat acne, seborrhoea, androgenic alopecia, and mild hirsutism in hirsute women, with its effectiveness influenced by the severity and duration of the condition.
June 2014 in “Reactions Weekly” January 2014 in “Reactions Weekly”