June 2026 in “International Journal of Ayurvedic Medicine (Hyderabad)” This study found that Facia Men’s capsule significantly reduced hair shedding in men with androgenetic alopecia over 12 weeks, without notable renal or liver safety concerns.
This study found that Clitocybin A from Clitocybe aurantiaca may promote hair growth in immortalized rat dermal papilla cells by enhancing cell proliferation and activating Wnt/β-catenin signaling and ERK pathways.
Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.
17 citations
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June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, FCE 28260 showed greater potency than finasteride in inhibiting 5α-reductase enzymes and reducing prostate DHT levels in rats.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that hydroxycinnamate derivatives, especially a compound named 10a, effectively inhibited SRD5A1 activity and protein expression in cell assays, suggesting potential for treating androgen-related conditions.
January 2020 in “Dépôt Institutionnel de lUniversité de Tlemcen” This article is primarily an acknowledgment and dedication section of a thesis, expressing gratitude to individuals involved in its completion and reports no new research findings.
78 citations
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August 2017 in “Endocrine Reviews” This review discusses the free hormone hypothesis for measuring "free" testosterone and critiques its theoretical basis and clinical application, noting it lacks critical empirical testing and has inconsistent utility in assessing androgen status.
January 2007 in “Inpharma Weekly” Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.
April 2014 in “Significance” Unconventional home remedies can sometimes show surprising results.
35 citations
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January 2010 in “British Journal of Clinical Pharmacology” This case report described a probable case of acute liver injury associated with high-dose S. repens, highlighting the safety concerns of self-medicating with herbal supplements like saw palmetto.
60 citations
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September 1979 in “Fertility and sterility” This study found that spironolactone reduced testosterone production and urinary 17-ketosteroid excretion, leading to a decrease in hair growth rate and a change in hair texture in women.
9 citations
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November 2019 in “Scientific reports” This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.
10 citations
,
February 1976 in “The Journal of Dermatology” This study found that topical γ‐Oryzanol significantly stimulated sebaceous gland cell activity and sebum production in rats.
13 citations
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January 2014 in “PubMed” In this study, A. capillus-veneris solution demonstrated potential to reduce hair loss and improve hair characteristics in a testosterone-induced alopecia mouse model.
This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets, requiring conversion to DHT and E2 via SRD5A1 and aromatase.
February 2023 in “riUfes (Universidade Federal do Espírito Santo)” This study found that supraphysiological doses of testosterone alter endothelial relaxation pathways in hypertensive rats, with varied contributions from nitric oxide, prostanoids, and endothelium-derived hyperpolarizing factors, influenced by estrogen and dihydrotestosterone levels.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the FitSpresso weight loss supplement's potential benefits and mechanisms but provides no clinical research findings; it reports on its ingredients and consumer ratings instead.
3 citations
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May 2021 in “Evidence-based Complementary and Alternative Medicine” This review discusses the potential antiaging effects of Chinese herbal medicines and suggests their role in regulating aging-related genes through various signaling pathways; it reports no new clinical results.
4 citations
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October 2020 in “Toxicology Mechanisms and Methods” This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
September 2023 in “Baylor University Medical Center Proceedings” This study reviewed the effectiveness of natural treatments like pumpkin seed oil and rosemary oil for androgenetic alopecia and found them potentially effective with minimal side effects compared to standard treatments like minoxidil. However, more research is needed to confirm their efficacy.
April 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study identified 64 chemical compounds in the L. luteus L. plant, including several fatty acids and coumarin, highlighting the pharmacognostic potential of yellow lupine.
1 citations
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January 2022 in “Italian journal of dermatology and venereology” This study found that a topical treatment combining arginine and zinc significantly reduced hair loss and increased anagen hair percentage in patients with androgenetic alopecia and telogen effluvium, suggesting it might be a promising alternative to finasteride.
6 citations
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January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.
12 citations
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January 2020 in “touchREVIEWS in Endocrinology” Testosterone may both worsen and protect against COVID-19 effects in men.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
25 citations
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December 2017 in “The Journal of Clinical Endocrinology & Metabolism” This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.
2 citations
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April 2023 in “Pharmaceuticals” This review discusses the controversial cardiovascular safety and efficacy of subcutaneous testosterone therapy in postmenopausal women, noting that its long-term use appears safe, but CV risk assessments remain disputed.
2 citations
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March 2016 in “The Journal of Urology” This study found that the 1 mg dose of finasteride was associated with a wide range of adverse effects, including sexual, psychological, and metabolic symptoms, in the FAERS data.
January 2018 in “Elsevier eBooks” This article discusses the hypothalamus-pituitary-testis axis in androgen production and spermatogenesis but presents no new research findings.
April 2014 in “Dermatology Times” This article reviews the potential mechanism of saw palmetto berries in blocking 5-alpha-reductase, similar to finasteride, but reports no new findings.