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Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Lowering testosterone speeds up wound healing in male mice.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.