6 citations
,
February 2025 in “Scientific Reports” This study found that MEGA PROTAC improved the prediction of ternary structures with higher maximum DockQ scores compared to the BOTCP method in 16 out of 22 test cases.
January 2024 in “Wiadomości Lekarskie” This study found that administering steroids alongside cochlear implantation using Skarżyński's six-step method helped preserve residual hearing in patients, with a higher hearing preservation rate observed in those receiving steroids compared to those without.
December 1992 in “Reviews in Medical Virology” The review concluded that restrictions on people with HIV/AIDS often violated their rights without proven effectiveness in stopping the virus, highlighting education as the best control method.
August 2016 in “International journal of scientific research” In this study, most male patients with androgenic alopecia who transitioned from oral to topical finasteride with minoxidil maintained good hair density.
169 citations
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May 2006 in “Genes & Development” This study found that keratin 17 and TNFα play interdependent roles in regulating hair follicle cycling, with TNFα required for the anagen–catagen transition and its ablation partially rescuing hair cycling defects in K17-null mice.
121 citations
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May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” This study reported the successful isolation of epithelial stem cells from mouse embryonic skin using a simple culture method, with the cells showing the potential to differentiate into multiple cell types.
32 citations
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April 2016 in “Aaps Pharmscitech” This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.
25 citations
,
October 2018 in “PloS one” This study explored hair follicle gene expression in Inner Mongolia Cashmere goats and identified potential regulators of the transition between growth phases, including IL17RB and ZNF genes.
22 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” This study found that resveratrol and fisetin promoted hair growth in mice by inducing telomerase reverse transcriptase expression, which activates hair follicle stem cells and transitions follicles from a resting to a growth phase.
20 citations
,
April 1999 in “British journal of plastic surgery” This study found that using a ruby laser for hair removal resulted in a significant average reduction of 56.4% in hair density among participants dissatisfied with other methods.
16 citations
,
January 2016 in “International Journal of Medical Sciences” This study found that Wnt5a suppresses β-catenin signaling, inhibiting the transition of hair follicles from the telogen to anagen phase.
13 citations
,
January 2018 in “BioMed Research International” This review summarizes recent findings on scalp involvement in pemphigus vulgaris and pemphigus foliaceus, highlighting diagnostic methods and their underlying histopathological, immunopathological, and clinical features, but reports no new clinical results.
13 citations
,
September 2002 in “Dermatologic Surgery” This article discusses various repair techniques for hair transplants, emphasizing meticulous methods to improve cosmetic outcomes when donor hair is limited, but it presents no new clinical results.
12 citations
,
April 2025 in “Discover Pharmaceutical Sciences” This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.
11 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that Blumea eriantha silver nanoparticles promoted hair growth in treated animals, with activity comparable to minoxidil in terms of anagen follicle transition.
9 citations
,
April 2000 in “Plastic and Reconstructive Surgery” This article describes a refined technique for improving hair transplant results by recycling oversized plugs into smaller grafts, integrating advanced methods like scalp lifting and occipital harvesting.
4 citations
,
June 2020 in “British Journal of Pharmacology” This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.
4 citations
,
January 2019 in “Elsevier eBooks” This review examines the current landscape of drug repositioning, highlighting that computational methods expand possibilities for reusing existing drugs to treat unmet medical needs. The authors discuss both the potential of these methods and the challenges faced in identifying new therapeutic applications.
3 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.
3 citations
,
June 2022 in “Plastic & Reconstructive Surgery” In this study, both endoscopic and pretrichial open forehead lifts were found to significantly elevate eyebrows long-term, with high patient satisfaction reported, showing no significant difference between the two methods.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.
3 citations
,
October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
2 citations
,
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers used an evolutionary-rate-based method to identify genetic elements associated with reduced hair in mammals, finding a dichotomy between accelerated coding sequences and noncoding regulatory elements influencing hair growth.
2 citations
,
February 2019 in “Journal of Investigative Dermatology” This study suggests that the expression of the DP2 receptor is higher in balding scalp cells and that its knockdown could inhibit the transition to the catagen phase in cultured human hair follicles, potentially counteracting hair growth inhibition associated with male pattern baldness.
1 citations
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April 2026 in “Cancer Nanotechnology” This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.
1 citations
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April 2025 in “Tropical Journal of Natural Product Research” In this study, researchers using network pharmacology and molecular docking methods found that compounds from Avicennia Marina could inhibit hepatitis C virus infection by targeting key proteins such as AKT1 and TNF-α, showing potential for anti-HCV treatments.
1 citations
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January 2023 in “Journal of pharmaceutical and biological sciences” This review examines ethosomal structures and their mechanisms as skin delivery systems, outlining preparation methods and applications but presents no new experimental findings.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
May 2026 in “Dermatology Online Journal” This review examined three studies on dermaroller monotherapy for hair loss, finding inconsistent efficacy and diverse methods, with risks of follicular damage and infection noted; standardized protocols are urgently needed for safe practice.