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Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

The HR protein's role as a repressor is essential for controlling hair growth.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

New treatments for skin and hair repair show promise, but further improvements are needed.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.

Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.

Micrografts improve hair density and thickness without side effects.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.

Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.

The conference highlighted new dermatological treatments and emphasized early intervention and addressing conditions lacking evidence-based treatments.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.