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Chromosomal differences affect how muscle cells respond to testosterone.

The document concludes that more inclusive research involving the transgender community is needed, especially on the neovaginal microbiome of trans women.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

The document concludes that facial feminization surgery improves psychological well-being and social acceptance for transgender individuals.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

More research is needed to improve lower body gender affirmation techniques.

Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Testosterone therapy in transgender men can lead to hair loss, with the risk increasing over time and influenced by family history.

Many transgender men on testosterone therapy experience hair loss.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.