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Chromosomal differences affect how muscle cells respond to testosterone.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

The document concludes that more inclusive research involving the transgender community is needed, especially on the neovaginal microbiome of trans women.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

The document concludes that facial feminization surgery improves psychological well-being and social acceptance for transgender individuals.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Many transgender men on testosterone therapy experience hair loss.

Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.

Feminizing hormone therapy increases kidney filtration rate.

Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.