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The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

New drug delivery systems improve treatment effectiveness and patient experience.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Microneedles with enhancer effectively promote hair growth and increase hair density.

Optimized film improves finasteride skin absorption and treatment efficiency.

Finasteride delivery through skin improved using invasomes and iontophoresis.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.

Testosterone's muscle-building effects do not require its conversion to DHT.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.

Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.

Convolvulus arvensis ethanolic extract can potentially promote hair growth and reduce hair loss.

Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.

The optimized microemulsion with cinnamon oil effectively delivers finasteride through the skin without damaging hair.

Cedrol nanoemulsions effectively treat hair loss by promoting hair growth and reducing DHT levels safely.

Exogenous testosterone use may be linked to developing hidradenitis suppurativa.

A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.