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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

ILK is essential for proper hair follicle development and structure.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The HR protein's role as a repressor is essential for controlling hair growth.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Androgens prevent hair growth by changing Wnt signals in cells.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

ΔNp63α helps control a protein that stops cancer cells from spreading.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.