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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Advanced human skin models improve drug development and could replace animal testing.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.