263 citations
,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.
70 citations
,
April 1990 in “Journal of The American Academy of Dermatology” Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.
8 citations
,
May 1987 in “Journal of The American Academy of Dermatology” In this study, ultraviolet light did not significantly enhance or worsen hair growth induced by topical minoxidil in men with male pattern baldness.
August 2026 in “Journal of Cosmetic Dermatology” This systematic review reported that both hair transplantation and topical minoxidil were associated with cosmetic improvement in patients with temporal triangular alopecia, but noted that the evidence is based on low-level studies and highlighted the need for higher-quality research, especially in pediatric populations.
4 citations
,
July 2022 in “Clinical and Experimental Dermatology” This review examines the efficacy and safety of using minoxidil at concentrations greater than 5% for androgenetic alopecia but reports no new clinical results, emphasizing a need for further research.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.
115 citations
,
November 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This review discusses the impact of sleep cycles and circadian rhythms on nighttime exacerbation of atopic dermatitis in children and presents potential treatment options for related sleep disturbances, but reports no new clinical results.
83 citations
,
June 2017 in “Journal of the American Academy of Dermatology” This study observed that most pediatric patients with alopecia areata experienced some hair regrowth after treatment with topical JAK inhibitors, and the formulations were generally well-tolerated with mild lab abnormalities in some cases.
72 citations
,
February 2011 in “The American Journal of Dermatopathology” This study found that anti-TNF therapy-induced alopecia exhibits distinct clinical and histopathological features and can mimic psoriatic alopecia and alopecia areata, with some patients improving with topical treatment.
56 citations
,
September 2016 in “Pharmaceutical Research” This study found that imiquimod combined with fish oil in a bigel formulation enhanced antitumor effects and reduced inflammatory side effects in a skin cancer model.
53 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
33 citations
,
February 2021 in “Journal of Medicinal Chemistry” This study found that novel MPC inhibitor analogues with specific chemical modifications promoted significant hair growth in shaved mice when applied topically.
32 citations
,
December 2017 in “International Journal of Molecular Sciences” This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.
26 citations
,
December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
26 citations
,
March 1994 in “Archives of Dermatology” This study found that a 2% topical minoxidil solution was significantly more effective than a placebo in promoting hair growth in women with androgenetic alopecia over 32 weeks.
26 citations
,
January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.
26 citations
,
January 1987 in “Dermatology” This study reported that topical 2% minoxidil solution improved hair growth compared to placebo in men with early male-pattern baldness over 24 weeks, with no significant safety issues observed.
20 citations
,
January 2013 in “Annals of Dermatology” Topical minoxidil successfully treated temporal triangular alopecia.
20 citations
,
March 1990 in “JAMA” This report from the National Registry of Drug-Induced Ocular Side Effects identifies 56 cases of alopecia associated with the use of topical ophthalmic β-blockers.
16 citations
,
July 1988 in “International Journal of Dermatology” This study found that 2% minoxidil solution significantly increased nonvellus hair count in men with male pattern baldness compared to placebo during a 48-week trial.
12 citations
,
October 2015 in “PubMed” This study found that topical minoxidil is more effective than placebo in promoting hair growth in androgenetic alopecia, although cosmetically acceptable results occur only in a subset of patients.
10 citations
,
May 2007 in “PubMed” This study found that 1% topical minoxidil significantly increased hair count and improved hair growth perception among Japanese women with androgenetic alopecia compared to placebo.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This article reviews the potential of topical minoxidil to cosmetically thicken hair in some individuals with male pattern hair loss, but it reports no new clinical results.
7 citations
,
September 1991 in “PubMed” This study found that 2 percent topical minoxidil significantly increased nonvellus hair count and showed moderate regrowth compared to placebo in women with mild to moderate androgenetic alopecia, although participants did not notice the difference.
5 citations
,
March 2016 in “Medical journal, Armed Forces India” This report describes a case of refractory shock and pulmonary edema resulting from the accidental ingestion of topical minoxidil, highlighting a rare instance of poisoning.
5 citations
,
October 1993 in “International Journal of Dermatology” This study found that 2% minoxidil led to moderate to dense hair growth in 80% of Middle-Eastern men treated for 48 weeks with early androgenic alopecia.
4 citations
,
December 2021 in “Vestnik dermatologii i venerologii” This review reported that various nonsurgical treatments, like cryosurgery, photodynamic therapy, and topical medications, offer effective alternatives for basal cell carcinoma management, especially when surgery is unsuitable, and treatment decisions should consider tumor characteristics and patient preferences.
3 citations
,
January 1987 in “Archives of Dermatology” This survey found that over 70% of dermatologists in the sample had prescribed topical minoxidil for hair loss, with low reported complications beyond local irritation.
2 citations
,
January 2020 in “Einstein (São Paulo)” This review discusses the potential of Janus kinase inhibitors as a promising new treatment for alopecia areata, suggesting they could become a first-line therapy in the future, but reports no new clinical results.
1 citations
,
February 2025 in “International Journal For Multidisciplinary Research” This study developed and validated a simple, accurate, and sensitive HPTLC method for estimating minoxidil and aminexil in topical solutions, demonstrating effective separation and linear measurement of these compounds with %RSD under 2% and high regression coefficients.