TLDR Topical eye β-blockers may cause hair loss.
The document reported the first cases of alopecia potentially caused by topical ophthalmic β-blockers, commonly used for glaucoma treatment. The National Registry of Drug-Induced Ocular Side Effects received 56 reports of alopecia in patients using timolol (48 cases), betaxolol (5 cases), or levobunolol (3 cases). The patients, mostly female and aged 33-86, experienced asymptomatic, diffuse, non-scarring hair loss on the scalp, eyelashes, and/or eyebrows, with 4 cases identified as alopecia areata. The alopecia typically resolved within 4-8 months after discontinuing the β-blockers. This suggested that physicians should consider topical ophthalmic β-blockers as a potential cause of alopecia in their differential diagnosis.
22 citations,
April 1985 in “Australasian Journal of Dermatology” Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.
33 citations,
August 1973 in “American Heart Journal” Propranolol can cause reversible hair loss.
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13 citations,
March 1990 in “JAMA” Topical eye β-blockers might cause hair loss, which usually gets better after stopping the medication.
Eye drops with β-blockers may cause hair loss.
[object Object] January 1993 in “Side effects of drugs annual” Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.
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April 2022 in “Biomedicine & pharmacotherapy” Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
31 citations,
April 2019 in “Experimental and Therapeutic Medicine” β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.