February 2025 in “Indian Dermatology Online Journal” This case report describes a rare occurrence of pincer nail deformity in a patient with systemic lupus erythematosus, potentially linked to Raynaud's phenomena as a contributing factor.
January 2025 in “Frontiers in Genetics” In this study, researchers reported significant hair growth in an 8-year-old with hypotrichosis simplex of the scalp after treatment with a combination of oral botanical extracts and minoxidil, marking the first documented use of botanical extracts as a potential therapeutic approach for this condition.
July 2024 in “Journal of Dermatological Treatment” In this case report, a 6-year-old boy with hidrotic ectodermal dysplasia 2 caused by GJB6 mutations showed no significant hair improvement with age, despite treatment with botanical extracts and Minoxidil.
July 2024 in “Biomolecular and Health Science Journal” This case report describes a 33-year-old woman with both subacute cutaneous lupus erythematosus and onychomycosis, highlighting the importance of excluding infections and considering the spectrum of alopecia causes in lupus patients.
September 2022 in “Indian Journal of Paediatric Dermatology” This case report documents the first confirmed mutation-proved instance of Clouston syndrome in a large Chinese-Malaysian family, linked to the c.263C>T (A88V) mutation in the GJB6 gene, with no available treatment but highlighting the importance of genetic counseling.
January 2023 in “Indian dermatology online journal” This case report discusses a 15-year-old boy with pachyonychia congenita, identifying a keratin 17 gene mutation, and highlights the need for a national registry and more accessible genetic testing in India.
15 citations
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March 2024 in “Journal of Clinical Medicine” In this four-year study, pediatric patients with inoperable plexiform neurofibromas and type 1 neurofibromatosis treated with selumetinib frequently experienced dermatologic side effects, which required tailored management strategies and sometimes led to treatment suspension, potentially affecting tumor regrowth.
4 citations
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October 2015 in “JAAD Case Reports” This case report describes a patient experiencing nail nonadherence due to sterile matrix scarring associated with valproic acid use, and suggests nail bed excision with sterile matrix grafting as a potential surgical solution.
3 citations
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July 2024 in “Frontiers in Medicine” This study reports that analyzing the clinical manifestations of different genetic variants in EBS families helps predict disease progression and severity, guide complication risk assessment, and plan necessary medical care.
1 citations
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March 2022 in “Frontiers in Medicine” This case report highlights a rare instance of esophageal carcinoma in a patient with Cronkhite-Canada syndrome, emphasizing the importance of endoscopic surveillance for malignant gastrointestinal tumors in these patients.
September 2025 in “International Journal of Emergency Medicine” This study reported that the increased dermatological emergency department visits during the pandemic, influenced by PPE usage and psychological stressors, highlight the need for more robust dermatology training and resources in emergency medicine to better prepare for future pandemics.
October 2023 in “Psychiatry research. Case reports” In this study, researchers observed that twins with a novel de novo nonsense variant in HRAS exhibited distinctive features, including neuropsychiatric symptoms, potentially indicating a wider clinical spectrum for conditions known as RASopathies.
22 citations
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February 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes severe skin and nail issues and hair loss.
2 citations
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August 2022 in “Frontiers in Immunology” This study reported significant hair regeneration in a 3-year-old with severe alopecia areata after six months of treatment with microneedling and compound betamethasone.
August 2023 in “Gastroenterology” This study describes the diagnosis and successful management of Cronkhite-Canada syndrome in a 78-year-old man, highlighting improvement in symptoms and endoscopic findings after treatment with prednisone and supportive therapies.
382 citations
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February 2010 in “Archives of Internal Medicine” This study identified that high concentrations of selenium in a liquid dietary supplement caused a widespread outbreak of poisoning, revealing the importance of stricter manufacturing standards.
139 citations
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October 2005 in “Journal of Investigative Dermatology” This study describes previously unknown immune characteristics of the normal human nail, highlighting its similarities to the hair follicle immune system and suggesting an immune privilege in the proximal nail matrix that both provides autoimmunity protection and presents infection susceptibility.
86 citations
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November 2020 in “Annals of Oncology” These guidelines discuss prevention and management strategies for dermatological toxicities but report no new clinical results; they include expert recommendations for conditions like acneiform rash and hand-foot syndrome.
50 citations
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January 1986 46 citations
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July 2022 in “Frontiers in Oncology” This review discusses recent advancements in cold atmospheric plasma therapies for dermatology, covering optimization, treatment of skin diseases, safety, and does not report new clinical outcomes; it calls for continued research in the field.
30 citations
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January 2023 in “EFSA journal” This review establishes a tolerable upper intake level of 255 μg/day for selenium in adults, warning that supplements and Brazil nuts may cause excess intake.
28 citations
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September 2013 in “Biogerontology” 22 citations
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September 2003 in “Journal of Investigative Dermatology” This study analyzed patients with X-linked dominant chondrodysplasia punctata and identified novel mutations in the emopamil-binding protein gene, highlighting the need for genetic testing alongside biochemical analysis for accurate diagnosis.
21 citations
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December 2022 in “Pharmaceutics” This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.
19 citations
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March 2008 in “Wound Repair and Regeneration” This article discusses the development of consensus-based guidelines for preventing lower extremity arterial insufficiency ulcers but reports no new clinical results.
6 citations
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February 2022 in “JAAD International” This systematic review found that hair loss was more frequently observed in acne patients on isotretinoin doses ≥0.5 mg/kg/d compared to those on lower doses, suggesting dose-dependent effects.
4 citations
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January 2019 in “Egyptian Journal of Dermatology and Venereology” This study suggests that androgenetic alopecia moderately affects quality of life, with women experiencing a higher impact and showing a greater willingness to pay for treatment than men.
1 citations
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February 2024 in “Pharmaceutics” This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.
January 2026 in “International Journal of Molecular Sciences” This study found that eyebrow follicles, as opposed to buccal swabs or nails, are the most reliable tissue for post-HSCT germline genetic testing due to lower donor DNA contamination.
December 2025 in “Dietetics” This paper reviewed studies from 2019 to 2025 on the use of olive oil and other derivatives from the European olive tree for skin, hair, and nail care, noting their roles in wound healing and skin aging while highlighting a favorable safety profile.