TLDR Surgical grafting may fix nail issues caused by valproic acid.
Valproic acid (VPA), commonly used for epilepsy and mood stabilization, was known to cause various skin-related side effects, including temporary hair loss. The document reported a case where a patient experienced nail nonadherence due to sterile matrix scarring while using VPA. The authors proposed a surgical intervention involving nail bed excision and sterile matrix grafting as a potential solution for this condition.
35 citations
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January 2006 in “Journal of Dermatological Treatment” Zinc can help with some skin problems, but its effectiveness varies depending on the condition.
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January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
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January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
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June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
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November 2018 in “Nutrients” Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
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October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.