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Most patients successfully switched from the original adalimumab to a biosimilar with few reverting due to reduced effectiveness or side effects.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Interleukin levels are higher in alopecia areata patients but don't predict disease severity or duration.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study aims to understand various diseases in older adults.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Overweight women with PCOS are more likely to have excess male hormones.

A new method accurately measures nine specific hormones in human blood.

Larger ovarian size is linked to higher insulin resistance in women with PCOS.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Lower growth factors linked to balding in androgenetic alopecia.

Melatonin given to pregnant rabbits improved their babies' fur quality.

The document explains how to do skin procedures, care after surgery, and when to use certain treatments.

Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

A woman's hair grew back after stopping acitretin for psoriasis and getting steroid treatment, and low vitamin D might be linked to alopecia severity.

Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.

Low ferritin levels are linked to increased hair loss; no link found between vitamin B12, TSH levels, and hair loss.

Certain factors like patchy hair loss at the back of the head, being female, and younger age at diagnosis can lead to a worse outcome for alopecia areata.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.