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Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Vitamin C derivative reduces hair loss-related protein in cells.

Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

A patch with curcumin-zinc can improve hair growth and health by delivering beneficial particles to the skin, increasing hair follicles, and reversing effects of a hair loss hormone.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Finasteride for hair loss is safe and does not increase the risk of high-grade prostate cancer.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Sex hormones affect brain cells differently in males and females.

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Fat-derived stem cells may help treat skin aging and hair loss.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.