45 citations
,
November 2022 in “Acta Biomaterialia” This study developed a biomimetic 3-D co-culture system that enhances the hair-inductive properties of human dermal papilla cell aggregates, potentially improving hair follicle tissue engineering.
20 citations
,
September 2022 in “Journal of Biomedical Optics” This article reviews the potential of using PBM in 3D tissue engineering to improve cell viability under stress conditions but reports no new experimental findings.
15 citations
,
January 2014 in “BioMed Research International” This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.
12 citations
,
February 2013 in “The Open Stem Cell Journal” This article reviews the definitions, opportunities, advantages, and limitations of dental pulp stem cells and stem cells from human exfoliated deciduous teeth in tissue engineering and regenerative medicine, reporting no new clinical results.
8 citations
,
May 2023 in “Gels” This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
8 citations
,
January 2023 in “RSC Advances” This article reviews advancements in carbon dots for tissue engineering and regenerative medicine, highlighting challenges and future directions without presenting new clinical findings.
3 citations
,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
July 2025 in “Frontiers in Bioengineering and Biotechnology” This study reports that despite advancements in tissue engineering and biomaterials, translating laboratory findings into effective clinical treatments for urethral reconstruction remains inadequate due to lack of standardization and short clinical trial follow-ups.
September 2023 in “Frontiers in bioengineering and biotechnology” This review explores the role of JAG1 in disease treatment, highlighting the need for effective methods to deliver JAG1 in its bound form to activate NOTCH signaling for therapeutic applications in craniofacial bone loss and myocardial infarction.
November 2022 in “Journal of Nanobiotechnology” In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.
27 citations
,
May 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This review discusses strategies and translational advancements in urethral tissue engineering, concluding that a combination of hypoxia-preconditioned mesenchymal stem cells on pre-vascularized synthetic scaffolds may be most effective; it reports no new clinical results.
This study reported that hydrogels created from keratins extracted from human hair exhibit antibacterial properties and enhance tissue regeneration, suggesting their potential use in full-thickness skin repair, as demonstrated by increased collagen production and improved healing in vivo.
February 2024 in “Tissue & Cell” This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
203 citations
,
May 2022 in “Pharmaceutics” This review discusses ongoing concerns and advancements in the use of gelatin as a biomaterial in tissue engineering, highlighting improved tissue mimicry through techniques like 3D bioprinting and suggesting a future focus on disease detection and diagnosis rather than treatment.
17 citations
,
August 2024 in “Discover Nano” This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.
15 citations
,
October 2020 in “Journal of Nanomaterials” This review discusses the potential of strontium-containing electrospun nanofibers for bone tissue engineering, outlining their effects on various cell types and highlighting current research challenges and future perspectives in the field.
15 citations
,
August 2008 in “Plastic & Reconstructive Surgery” This review examines the emergence of new adult stem cell sources with potential for bone tissue engineering and discusses their advantages over traditional sources.
14 citations
,
March 2016 in “Regenerative Biomaterials” This article proposes a broad interpretation of tissue engineering as systematically controlling the body's cells, matrices, and fluids, suggesting many existing therapies may fall under this category.
7 citations
,
January 2019 in “Methods in molecular biology” This chapter describes methods for creating engineered skin substitutes with chimeric hair follicles using human and murine cell grafts in immunodeficient mice, but reports no clinical outcomes.
5 citations
,
November 2024 in “Biomedicine & Pharmacotherapy” This study developed a carbohydrate chitosan-based biomaterial combined with a novel peptide to promote the chondrogenic differentiation of human adipose-derived stem cells, suggesting potential clinical applications for cartilage regeneration.
1 citations
,
March 2024 in “Nanomaterials” This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.
September 2025 in “Journal of Polymer Science” This review article highlighted the diverse applications of functionalized materials from bacterial cellulose, detailing advances in both in situ and ex situ methods for enhancing these materials' properties, particularly for medical applications, and proposed directions for future research.
July 2023 in “BENTHAM SCIENCE PUBLISHERS eBooks” This book chapter reviews the subclasses and applications of platelet-rich plasma in tissue engineering and highlights the challenges in clinical translation without reporting new clinical results.
73 citations
,
October 2022 in “Materials Today Bio” This review discusses the potential of baghdadite ceramic for biomedical applications such as coatings and scaffolds, and reports no new experimental findings, emphasizing its promising properties and need for further research.
49 citations
,
January 2023 in “Gels” This review summarizes recent advancements in three-dimensional bioprinting technology and hydrogel bioinks, highlighting their applications in tissue engineering, but reports no new experimental results.
40 citations
,
July 2024 in “Bioengineering” This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.
6 citations
,
April 2025 in “Plastic and Aesthetic Research” This review highlights that biomaterial properties can be designed to modulate macrophage activity, potentially reducing foreign body responses and enhancing tissue healing in regenerative medicine.
December 2025 in “Journal of Pharma Insights and Research.” This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.