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Low selenium levels can extend lifespan but worsen health issues.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Metformin is less effective in men with early-onset hair loss.

Women with PCOS often have sleep problems, including sleep apnea, which are linked to obesity and depression.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

PCOS is a long-term condition that needs more research for better understanding and treatment.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Combining Traditional Chinese Medicine and Western medicine can improve symptoms, hormone levels, and pregnancy outcomes in Polycystic Ovary Syndrome patients, but more research is needed.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

Acanthosis nigricans in teenage girls with PCOS is a sign of obesity, not insulin resistance or glucose intolerance.

Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Pregnancies in a woman with the Donohue mutation were managed with genetic testing, resulting in three healthy infants.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.