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Hormonal contraceptives and therapies regulate organ functions and treat various conditions.

This article reports a case of hair loss and pigmentation changes in a man after using propylthiouracil alongside iodine solution for thyroid and diabetic conditions, providing clinical observations without broader conclusions.

This study found that thyroxine modulates peripheral molecular clock gene expression in human hair follicles, which may have implications for treating clock-related diseases in patients with thyroid dysfunction.

This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.

This case report describes a 46-year-old female diagnosed with hypothyroidism, presenting with symptoms including severe hair loss, and treated with levothyroxine and supplements.

This study demonstrated that thyroid hormone receptors play a crucial role in hair growth and skin health, as mice lacking these receptors showed impaired hair cycling and wound healing.

This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.

This report describes cases of transient thyrotoxicosis potentially linked to oral retinoid treatment, suggesting a possible mechanism involving increased iodine uptake by thyroid cells.

This review discusses the diagnosis, management, and hormone treatment of transsexual individuals, and examines the risks and effects of cross-sex hormone therapy without presenting new clinical results.

This study suggests that adding androgens to menopausal hormone therapy may reduce breast cancer risk by counteracting estrogen-driven proliferation in postmenopausal breast tissue.

This study found that endocrine therapy for breast cancer is associated with a pattern of hair loss similar to androgenetic alopecia, negatively impacting quality of life despite mild severity.

This report presents a case of refractory thyrotoxicosis where the patient required a total thyroidectomy after resistance to conventional treatments including antithyroid drugs and radioactive iodine.

This research investigated the design and synthesis of steroid-based compounds as aromatase inhibitors for breast cancer, finding that certain structural modifications significantly enhance their inhibitory potency.

This article discusses the complexities of androgen and antiandrogen therapies in women, detailing diagnostic measures, the effects on libido, and the potential benefits of new progestins with antiandrogenic properties, but presents no new empirical findings.

This case report describes the use of individualized homoeopathic treatment and dietary modifications to manage hypothyroidism in a 23-year-old woman, resulting in symptom improvement and normalized TSH levels after tapering off levothyroxine.

This case report describes an unusual instance of myxedema in a woman with severe hypothyroidism, presenting with skin findings in atypical locations and improvement following levothyroxine treatment.

This study observed that levothyroxine therapy in men with autoimmune hypothyroidism was less effective at reducing thyroid antibodies and hormone disruptions in those with early-onset androgenetic alopecia compared to those without hair loss.

This study suggests that antiandrogens may slightly reduce hirsutism severity compared to placebo, but evidence is weak and their relative efficacy remains uncertain.

In this study, cyproterone acetate was found to be effective in treating 'idiopathic' hirsutism, while a combination of ethinyloestradiol and lynoestrenol reduced hair growth in fewer patients despite uniformly lowering testosterone levels.

This study found that applying supraphysiologic doses of topical T3 significantly accelerated wound healing in mice compared to a control vehicle, suggesting its potential as a cost-effective wound treatment.

This study reports that newly synthesized steroidal trienones exhibit higher 5α-reductase inhibitory activity than dienones in various biological models, suggesting potential use in treating androgen-dependent diseases.

In this study of a postmenopausal woman with hyperandrogenism, GnRH agonist treatment significantly reduced testosterone levels, suggesting the androgen excess was ovarian in origin and indicating the potential of using GnRH agonists as a conservative treatment option when surgery is not feasible.

A woman experienced excessive hair growth after using a hair loss treatment with minoxidil.

This integrative review found that while hormone therapy, under proper medical supervision, can improve quality of life by treating conditions like muscle and bone mass loss, using these hormones without clinical need poses serious risks to neurological, cardiac, hepatic, renal, and reproductive health.

This study found that two novel nonsteroidal derivatives inhibited specific enzymes in vitro and in vivo, leading to dihydrotestosterone accumulation in androgen-dependent glands, suggesting potential therapeutic use for mood improvement in the elderly.

This article discusses the effectiveness and indications of sex hormone therapy for various skin disorders and emphasizes the importance of avoiding androgen-effective contraceptives, but reports no new clinical results.

This study found that forsythoside A, a compound from Forsythia suspensa, may counteract DHT-induced hair regrowth inhibition by selectively inhibiting TRPV3 channels.

In this report, a 47-year-old woman with subclinical hypothyroidism experienced significant symptom relief and normalized TSH levels after six months of individualized homeopathic treatment with Sepia 1M, targeted to her symptom profile.

In this study, treatment with the oral contraceptive containing 30 μg ethinyl oestradiol and 150 μg desogestrel significantly reduced androgen-dependent hair growth in hirsute women over one year.