January 2019 in “Durham e-Theses (Durham University)” This study found that JNK plays a dominant role in hair follicle matrix density-dependent proliferation and differentiation, suggesting that collagen bundling affects keratinocyte dynamics.
This study measured the force required to pluck anagen and telogen hair from volunteers, suggesting that trichotillometry could assess hair strength in alopecia patients and evaluate treatment efficacy.
6 citations
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June 2024 in “Biofabrication” This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.
8 citations
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February 2002 in “Journal of Medical Genetics” In this study, synchrotron fibre diffraction identified changes in dermal collagen microfibrillar radius with age, with lower radii observed in individuals with insulin-dependent diabetes mellitus.
4 citations
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March 2015 in “Skin Research and Technology” This study suggests that using trichotillometry to establish the normal range of shear strain for different hair types could inform diagnostic and treatment decisions for various hair conditions.
February 2009 in “Journal of The American Academy of Dermatology” This pilot study found that fractional infrared technology improved skin laxity and thickness in the cervical area of four female patients without causing adverse effects.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
116 citations
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April 1986 in “The journal of cell biology/The Journal of cell biology” This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.
July 2018 in “Hair transplant forum international” This commentary discusses donor area alopecia resulting from follicular unit excision, noting that numerous small scars can lead to thinning in the donor area, and calls attention to this emerging issue.
6 citations
,
February 2016 in “American Journal of Dermatopathology” This case study reports on an 11-year-old boy with woolly hair nevus, featuring twisted hair shafts and an abnormal hair cuticle, alongside epidermal nevi on his face and back.
The guide suggests using keratin fibers and wigs to help hair look thicker or hide hair loss.
2 citations
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November 2017 in “Cardiovascular endocrinology” This study found that androgenic alopecia is the strongest predictor of coronary artery disease in young men from Western India, followed by premature graying and obesity.
32 citations
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June 1976 in “JAMA” In this study, nine individuals who underwent rigorous weight loss programs experienced significant hair loss, which researchers attributed to insufficient energy supply to the hair matrix, with regrowth occurring within months.
June 2022 in “Our Dermatology Online” In this study, researchers found that trichoscopy helps detect early signs of female-pattern hair loss before it is visible, highlighting its importance for monitoring and managing the condition.
15 citations
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December 1972 in “Journal of Investigative Dermatology” January 2022 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that applying SERUM THICKER increased hair density significantly over six months in individuals with mild to moderate androgenetic alopecia, with greater efficacy from daily use.
December 2015 in “Dermatologic Surgery” Double trichophytic closure effectively repairs thin scalp scars, reducing financial burden.
4 citations
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March 2021 in “International Journal of Environmental Research and Public Health” This study found that women with polycystic ovary syndrome have higher body mass index, fat mass percentage, and skinfold thickness compared to women without PCOS.
This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.
March 2023 in “Journal of Personalized Medicine” During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.
September 1989 in “PubMed” This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.
1 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that knocking out vinculin in mouse skin disrupts bulge stem cell quiescence by impairing force generation and mechanical stability of adherens junctions.
135 citations
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December 2006 in “PLoS Medicine” This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.
117 citations
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August 2005 in “Ultramicroscopy” This study systematically characterized the nanomechanical properties of human hair, such as hardness and elastic modulus, across different ethnicities and treatment conditions using nanoindentation and scanning electron microscopy.
1 citations
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November 2022 in “Pharmaceutical research” In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.
13 citations
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April 2023 in “Biochemical Society Transactions” This mini-review highlights emerging themes on how tissue stiffness, a fundamental material property, influences morphogenetic processes in living organisms, an area gaining increased attention alongside the role of mechanical forces in shaping cell behavior.
September 2023 in “Journal of the turkish academy of dermatology” In this study, researchers found that men with androgenetic alopecia had higher obesity-related parameters, such as fat percentage and BMI, compared to healthy controls, but observed no differences in cardiovascular markers like CIMT and EFT.
47 citations
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October 2020 in “Communications Biology” This study found that maintaining tension-force balance in a human skin equivalent improved characteristics of skin homeostasis and structure, suggesting potential as an alternative to animal models for studying skin physiology.
20 citations
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April 2002 in “PubMed” In this study, mini rats with reduced growth hormone and insulin-like growth factor-1 levels exhibited distinct differences in skin thickness and hair cycle compared to standard Wistar rats, suggesting potential use as an animal model for studying GH deficiency-related skin conditions.