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MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Fat-related cells are important for initiating hair growth.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

Corporate social responsibility can improve consumer ratings of product performance, especially when the company is seen as benevolent and consumers aren't experts on the product.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Histamine plays key roles in immune responses, stomach acid, and brain signals.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Porcine skin is very similar to human skin, making it a useful model for research.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.