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The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

TGF-β2 plays a key role in human hair growth and development.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Cyclosporin doesn't stop hair loss.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Terbinafine can cause hair loss.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

The local environment is crucial for cell development in the tongue.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.