research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
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research Current and Potential Agents for the Treatment of Alopecia Areata
Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
research Expression Profiling Reveals Genes Involved in the Regulation of Wool Follicle Bulb Regression and Regeneration in Sheep
The research identified genes and pathways important for sheep wool growth and shedding.
research An In Vitro Model for the Study of Human Hair Growth
Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
research Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research From Hair to Liver: Emerging Application of Hair Follicle Mesenchymal Stem Cell Transplantation Reverses Liver Cirrhosis by Blocking the TGF-β/Smad Signaling Pathway to Inhibit Pathological HSC Activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
research Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients
Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin affects certain genes and pathways involved in cashmere goat hair growth.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
research Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors
The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Leflunomide: An Unlikely Trigger and Mechanistically a Beneficial Drug for Alopecia Areata
Leflunomide is more likely to help treat alopecia areata than cause it.
research The Role of Activins and Follistatins in Skin and Hair Follicle Development and Function
Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
research Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes
Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
research Hair Sciences: The Hair Cycle Discussed with Dr. Gilliam Westgate
Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus
Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Role and Mechanisms of Phytochemicals in Hair Growth and Health
Natural products and phytochemicals may help with hair regrowth, but more research is needed.
research Co-Opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
research Rps14 Upregulation Promotes Inner Ear Progenitor Proliferation and Hair Cell Regeneration in the Neonatal Mouse Cochlea
Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.
research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Hair Follicle Stem Cells: The Signaling Hub of the Skin
Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration
Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
research Increment of Growth Factors in Mouse Skin Treated with Non-Thermal Plasma
Non-thermal plasma treatment makes mouse skin thicker and increases growth factors without harming the tissue.